nicking response catalysed with the MobA89K and MobC89K proteins. The cleaved strand is then unwound because of the helicase and delivered to the 89K-encoded GI-style T4SS equipment. The VirB1-89K element is thought to act as a lytic transglycosylase, domestically opening the peptidoglycan with contributions from Several other factor(s) in the cour